Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [8] [9] [10] For acne, it is applied to the skin as a …

All-trans-retinoic acid acts by binding to the retinoic acid receptor (RAR), which is bound to DNA as a heterodimer with the retinoid X receptor (RXR) in regions called retinoic acid response …

All-trans-retinoic acid (RA) plays crucial roles in a wide variety of biological processes including embryonic morphogenesis and organogenesis, cell proliferation, differentiation and apoptosis, …

Aug 5, 2021 · All-trans-retinoic acid (ATRA) is effective for preventing cancer and treating skin diseases and acute promyelocytic leukaemia (APL). These pharmacological effects of ATRA …

All-trans retinoic acid (ATRA) is an active metabolite of vitamin A under the family retinoid. Retinoids, through their cognate nuclear receptors, exert potent effects on cell growth, …

A nutrient that the body needs in small amounts to function and stay healthy. All-trans retinoic acid is made in the body from vitamin A and helps cells to grow and develop, especially in the embryo.

Dec 6, 2014 · Because ATRA can significantly mitigate disseminated intravascular coagulopathy (DIC), one of the early complications of APL, the NCCN and ELN guidelines support the …

Feb 27, 2023 · Tretinoin (Vesanoid®, All-Trans-Retinoic Acid, ATRA) is used in the treatment of acute promyelocytic leukemia.

It works by slowing down the growth of cancer cells. It belongs to a group of medications called retinoids. This medicine may be used for other purposes; ask your health care provider or …

All-trans-retinoic acid (atRA) provides essential support to diverse biological systems and physiological processes. Epithelial differentiation and its relationship to cancer and …