rmdopen.bmj3d
Methotrexate effect on immunogenicity and long-term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial
Objectives Anti-drug antibodies (ADA) are responsible for decreased adalimumab efficacy in axial spondyloarthritis (SpA). We aimed to evaluate the ability of methotrexate (MTX) to decrease adalimumab ...
rmdopen.bmj6d
Do we need bone mineral density to estimate osteoporotic fracture risk? A 10-year prospective multicentre validation study
Objective Evaluate the performance of FRAX®, with and without bone mineral densitometry (BMD), in predicting the occurrence of fragility fractures over 10 years. Methods Participants aged ≥40 years at ...
rmdopen.bmj9d
Achieving sustained minimal disease activity with methotrexate in early interleukin 23-driven early psoriatic arthritis
1 Department of Rheumatology and Clinical Immunology, Maasstad Hospital, Rotterdam, Netherlands 2 Department of Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands Objectives Methotrexate ...
rmdopen.bmj10d
Polymyalgia rheumatica: an autoinflammatory disorder?
Polymyalgia rheumatica (PMR) is an elderly onset syndrome characterised by aching and stiffness in the shoulders and the pelvic girdle associated to increased levels of acute phase reactants and rapid ...
rmdopen.bmj12d
Lymph nodes as gatekeepers of autoimmune diseases
3 Amsterdam Institute for Immunology and Infectious diseases, Amsterdam, The Netherlands 4 Amsterdam Rheumatology and Immunology Centre (ARC), Amsterdam, The Netherlands Secondary lymphoid organs such ...
rmdopen.bmj12d
Artificial intelligence in rheumatology research: what is it good for?
Artificial intelligence (AI) is transforming rheumatology research, with a myriad of studies aiming to improve diagnosis, prognosis and treatment prediction, while also showing potential capability to ...
rmdopen.bmj12d
Impact of ultrasound limitation to assess aortitis in patients with giant cell arteritis: comparative study with FDG-PET/CT
Objective To determine the impact of ultrasound (US) intrinsic limitation to assess aortitis versus FDG-PET/CT in patients with US-proven giant cell arteritis (GCA) and to identify factors associated ...
rmdopen.bmj12d
Impact of hyperuricaemia on patients with psoriatic arthritis treated with secukinumab in the FUTURE 2–5 and MAXIMISE studies
Objectives Patients with psoriatic arthritis (PsA) are at a significantly increased risk of hyperuricaemia and development of gout, and those with hyperuricaemia have been found to respond poorly to ...
rmdopen.bmj12d
High prevalence of radiographic erosions in early, untreated PsA: results from the SpARRO cohort
Aims To investigate the prevalence and distribution of bone erosions in an early psoriatic arthritis (PsA) population using conventional radiography (CR) and to explore the agreement between CR and ...
rmdopen.bmj28d
Low apolipoprotein A1 and high apolipoprotein B levels indicate specific lipid changes in treatment naïve early psoriatic arthritis
Objectives To investigate serum lipid profile in early, treatment-naïve psoriatic arthritis (PsA) and to determine whether changes in classical lipids or apolipoproteins are specific to PsA. Methods ...
rmdopen.bmj1mon
Use of artificial intelligence in imaging in rheumatology – current status and future perspectives
After decades of basic research with many setbacks, artificial intelligence (AI) has recently obtained significant breakthroughs, enabling computer programs to outperform human interpretation of ...
rmdopen.bmj1mon
Association between infection and the onset of giant cell arteritis and polymyalgia rheumatica: a systematic review and meta-analysis
Objective We aimed to analyse the association between infections and the subsequent risk of giant cell arteritis (GCA) and/or polymyalgia rheumatica (PMR) by a systematic review and a meta-analysis of ...