Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

San Francisco 49ers' stars George Kittle and Fred Warner are dealing with injuries, and here is the latest on their playing ...

The San Francisco 49ers (2-2) have 14 players listed on their injury report as they prepare to square off against the Arizona ...

Amid what constitutes scalding conditions for Northern California, 49ers coach Kyle Shanahan told reporters Friday that the ...

There is a slight chance that Fred Warner and George Kittle aren't available for the 49ers against the Cardinals in Week 5.

The 49ers are already seeking relief for players and fans ahead of Sunday’s game at Levi’s Stadium, where the kickoff ...

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

According to AccuWeather, the high for Sunday's Cardinals-49ers game will be 99 degrees, which wouldn't be anything new if ...

Unsurprisingly, the 49ers lead the all-time series between these two teams. Surprisingly, they only lead 36-29 — a ...

Kyler Murray and the Arizona Cardinals (1-3) have not been consistent and are banged up on the offensive line, but they have ...

San Francisco 49ers general manager John Lynch spoke on Friday about the team's contingency plan in case Fred Warner is out ...

A matchup with the offensively challenged New England Patriots was just what the San Francisco 49ers' defense needed to get ...