The San Francisco 49ers, along with their fans, are preparing for what is expected to be the hottest gametime temperature in ...

The 49ers must overcome not only temperatures in the 90s but do so against an Arizona team with offensive firepower.

The Arizona Cardinals got a significant injury boost Friday, as head coach Jonathan Gannon announced that tight end Trey ...

Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

Unsurprisingly, the 49ers lead the all-time series between these two teams. Surprisingly, they only lead 36-29 — a ...

Budda Baker will make his 100th career NFL start for the Arizona Cardinals on Sunday amid rumors he might be dealt before the ...

The San Francisco 49ers (2-2) have 14 players listed on their injury report as they prepare to square off against the Arizona ...

Head coach Kyle Shanahan told reporters Friday that the team put in a request to the NFL to switch from their usual red home ...

ARIZONA -- The Arizona Cardinals and San Francisco 49ers have released their final injury report of the Week 5 practice slate ...

The Arizona Cardinals take on the San Francisco 49ers Sunday afternoon at Levi's Stadium at 4:05 p.m. ET with the Cardinals ...

San Francisco 49ers general manager John Lynch spoke on Friday about the team's contingency plan in case Fred Warner is out ...