Scientists have used gene editing to produce artificial electrical synapses in mice, where they can be targeted to make the ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.

in which an electrical signal triggers the release of neurotransmitters at a synapse, which in turn triggers a new electrical ...

Second, the synapses that mediate these connections can be functionally very different, even when they belong to the same axon and contact the same postsynaptic target. What is the basis for this ...

Synapses are subcellular microcompartments that are essential for a digital form of transneuronal communication, mediated by chemical mediators termed neurotransmitters. At excitatory synapses in ...

The brain really is an incredible organ, and neurons are the vital link between, well, everything. The brain is anything but set in stone; how we think, feel, reason, and understand the world changes ...

The action potential causes the release of molecules called neurotransmitters, which pass from one end of the synapse to the other. Once these molecules cross the synapse, the chemical signal is ...

When an electrical signal arrives at the presynaptic terminal, neurotransmitters are released from vesicles into the gap between neurons. The neurotransmitters then trigger an electrical signal in ...

Neurons’ complex structures enable them to receive and transmit signals across synapses. McCabe’s team is interested in a specific part of this structure: the synaptic boutons, zones at the end of ...

The paper S. Holler et al., “Structure and function of a neocortical synapse,” Nature, doi:10.1038/s41586-020-03134-2, 2021. Brain cells use a language of ...

Recreational drugs can affect neurotransmitters in the reward pathway within the brain. They can act as either agonists or antagonists. Recreational drugs can also stimulate the release of ...