GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now. GLP-1s currently used for weight loss—although not all are expressly approved for this purpose—include Ozempic and Wegovy (semaglutide),

However, a third drug also FDA-approved for weight loss, liraglutide (Saxenda), didn’t work as well as the others, researchers found after reviewing data from dozens of clinical trials. The review also found that a GLP-1 drug still in development,

In one corner, we’ve got Mounjaro, and in the other, Ozempic. They’re both once-a-week injectable drugs designed to help patients with type 2 diabetes manage blood sugar.

From science-backed supplements to insurance-covered nutrition therapy, here's your complete guide to effective weight loss when Ozempic isn't an option.