Johns Hopkins Medicine scientists say they have found a pattern of so-called epigenetic "marks" in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may ...

The study is useful for advancing spatial transcriptomics through its novel regression-based linear model (glmSMA) that integrates single-cell RNA-seq with spatial reference atlases, though its ...

Digestive enzymes are found in the digestive system, including the mouth, stomach, and small intestine. They help you break down food and absorb nutrients. Sometimes, the body cannot make enough ...

Acute pancreatitis is a serious condition that causes the pancreas to become inflamed. It develops suddenly and can cause severe pain in the upper abdomen, often spreading to your back or left ...

Immunofluorescence images showing that cells with higher levels of the cancer-promoting MYC protein (red) also tend to exhibit high levels of DNA damage (green), suggesting that too much MYC leads ...

The significance of the findings is valuable, with implications for immunotherapy design in pancreatic ductal adenocarcinoma. The evidence was considered incomplete and partially supportive of the ...

In preclinical models, researchers identified a key molecular mechanism by which stress and obesity trigger changes in pancreatic cells that may lead to cancer. Specifically, stress-related ...

Gastrointestinal cancer refers to malignant conditions of the gastrointestinal (GI) tract and other organs involved in digestion, including the oesophagus, stomach, biliary system, pancreas, small ...

Introduction: The pancreas plays a crucial role in digestion and blood glucose regulation. Current animal models, primarily mice and zebrafish, have limited the exploration of pancreatic biology from ...

Radiation treatment is one of the most frequently used therapies in patients with cancer, employed in approximately half of all patients. However, the use of radiation therapy is limited by acute or ...