Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

HDAC6 is upregulated in corneal diseases and causes ENKD1 deacetylation at lysine 98. Deacetylation of ENKD1 blocks its ...

Epithelial thickness patterns can not identify subclinical keratoconus, although they exhibit predictable patterns in manifest keratoconus.

Cervical specimens for liquid-based cytology were collected and processed to prepare ... no intraepithelial or malignant lesions (NILM); (2) squamous epithelial cell abnormality: a, atypical squamous ...

The stem cell treatment for blinding cornea injuries — called cultivated autologous limbal epithelial cell (CALEC) transplantation — was developed at Mass Eye and Ear. It consists of removing stem ...

You, me, and all of the 108 billion or so Homo sapiens who’ve ever walked the Earth have all been our own constellation of some 30 trillion cells. Each of our bodies is a collective organism of ...

Intestinal epithelial cells (IECs) are a mucosal immune barrier essential to coordinate host–microbe crosstalk. Sepsis is a systemic inflammatory syndrome with dysfunction in multiple organs including ...

We developed computational and experimental approaches to quantify, with both sub-cellular and multi-cellular resolution, the dynamics of force transmission in cell clusters. Applying this technology ...