Steven Kliewer (The Salk Institute, La Jolla, Calif.): "Vitamin D, thyroid hormone, and all-trans retinoic acid are essential cofactors in development, differentiation, and homeostasis. The effects of ...

all-trans retinol is considered to be a parent ... their activities by interacting with nuclear receptors (RARs [retinoic acid receptors] or RXRs [retinoic X receptors]) on cells and by activating ...

And in 2018, all-trans retinoic acid (ATRA), a vitamin A derivative, together with the injection of ATO, was approved by the Food and Drug Administration of the United States. How do ATRA and ATO ...

However, not all retinoids are created equal ... It’s converted into retinoic acid, the active form of vitamin A, more ...

Phase II single-arm, single-center clinical trial of all-trans-retinoic acid, bevacizumab, and atezolizumab in refractory microsatellite stable colorectal cancer. A phase 3 study of first-line ...

Dr Zhenyi Wang and Dr Tingdong Zhang — Winners of the 2020 Life Science Prize The laureates were awarded the prize for their discoveries of the therapeutic effects of arsenic trioxide and all ...