Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

Also listed as questionable were tight end George Kittle (ribs) and cornerback Isaac Yiadom. Also questionable was wide ...

Amid what constitutes scalding conditions for Northern California, 49ers coach Kyle Shanahan told reporters Friday that the ...

San Francisco 49ers' stars George Kittle and Fred Warner are dealing with injuries, and here is the latest on their playing ...

The missing element? It’s sticking out like a sore Achilles. McCaffrey’s absence underscores just how essential he was to the ...

There is a slight chance that Fred Warner and George Kittle aren't available for the 49ers against the Cardinals in Week 5.

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

According to AccuWeather, the high for Sunday's Cardinals-49ers game will be 99 degrees, which wouldn't be anything new if ...

Unsurprisingly, the 49ers lead the all-time series between these two teams. Surprisingly, they only lead 36-29 — a ...

On Sunday in San Francisco (Santa Clara), record heat for early October is expected. With a projected high of 95, the 49ers ...

Kyler Murray and the Arizona Cardinals (1-3) have not been consistent and are banged up on the offensive line, but they have ...

A matchup with the offensively challenged New England Patriots was just what the San Francisco 49ers' defense needed to get ...