The Patriots enter their Week 4 matchup against San Francisco 1-3, coming off a deflating 24-3 loss to the Jets. The 49ers ...

This is the live blog for the San Francisco 49ers' Week 4 home game against the New England Patriots. I will update this ...

Linebacker Anfernee Jennings, who was questionable with a shoulder injury, has been officially ruled out for the Week 4 game.

SportsLine's model simulated New England Patriots vs. San Francisco 49ers 10,000 times and made its Week 4 NFL picks, ...

Not suiting up Sunday is safety Talanoa Hufanga who rolled his ankle in practice Thursday. Hufanga returned in Week 3 after ...

The Patriots look to reach .500 for the first time in years as they take on the 49ers in California. Follow along for live ...

San Francisco 49ers wide receiver Deebo Samuel (calf) is active for Sunday's Week 4 game against the New England Patriots.

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Will the defense rebound in Week 4 against San Francisco? Plus updates on Drake Maye, Oshane Ximines and Cole Strange.

According to Ian Rapoport, rookie Drake Maye might have to wait a bit longer before starting for the Patriots.

How close is Drake Maye to starting for the Patriots? Albert Breer shares two factors in consideration for the team regarding ...

San Francisco 49ers star George Kittle used "Yankee Doodle" as the opening of a hype video ahead of Sunday's game against the ...