When cells divide there is a substantial risk of genetic harm After all the cell must repeat its whole genetic material including billions of genetic letter ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response.

Every two minutes in the United States a woman is diagnosed with breast cancer, with approximately one in eight women ...

Patients with soft tissue sarcomas showed improved functional results, quality of life and fewer side effects when treated ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...

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A malignant neoplasm, or cancerous tumor, usually grows rapidly and can spread into other parts of the body, such as the lymphatic system, blood, or bone marrow. This is part of a process known as ...

The physical and molecular structure of brain tumors has made treatment difficult in the past. The complex nature of the brain frequently makes full surgery challenging, and the blood-tumor barrier ...

Although rare, bone cancer is a serious health concern that affects thousands of people annually. Knowing the early warning ...

A clinical trial supported by the National Institutes of Health (NIH) was stopped early after researchers found sufficient evidence that a drug used to treat bone marrow cancer and Kaposi sarcoma ...

A 45-year-old woman was evaluated in the rheumatology clinic because of possible IgG4-related disease. She had polyclonal ...

Investigators developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to ...