By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Discover how the brain's most abundant neurotransmitter, glutamate, is revolutionizing psychiatry and offering new hope for ...

Stimulant medications activate underperforming neural circuits in the prefrontal cortex” - Dr. Stanford OwenGULFPORT, MS, UN ...

A Nigerian researcher, Isreal Onifade, has identified plant compounds that could help in the treatment of Alzheimer’s disease.

Howard Hughes Medical Institute-led research has produced a complete connectome of the Drosophila visual system, enabling systematic investigations into how visual information is processed and relayed ...

Jennifer Morgan, senior scientist at the Marine Biological Laboratory, Woods Hole, studies how the synapse malfunctions in devastating diseases such as Parkinson’s and Lewy body dementia. Now, her lab ...

A fluorescent probe designed to incorporate a fluorophore into the structure of a neurotransmitter finds activity-dependent heterogeneity in dopamine release at individual synapses ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from ...

Pain is a complex physiological and psychological phenomenon that is subjective in nature. Pain is still one of the most ...

Are artificial neurons underestimating the power of their biological models? Ten years after initial theoretical predictions, ...

Here, we explored how NMDARs signal in tLTD. We found that, regardless of frequency, L5 PC→PC tLTD relies on the non-ionotropic preNMDAR signaling pathway mediated by JNK2, which helps to resolve the ...

Physicians have long observed a mystifying phenomenon: After a bout of infection or an autoimmune disease flare-up, some ...