Neural activity determines which synapses are preserved ... Excessive pruning is associated with schizophrenia, leading to reduced synaptic connectivity, while insufficient pruning may contribute ...

A recent study from Northwestern University has uncovered a genetic factor that may play a key role in autism. Researchers found that a specific gene affects how brain cells form connections during ...

Cannabis appears to aggravate already decreasing nerve connectivity in young adults at risk of psychosis, a new study has ...

Cannabis is a known risk factor for developing psychosis that can progress to schizophrenia but this ... s natural process of refining and pruning synapses, which is essential for healthy brain ...

2020). LASP1 encodes a protein found in synapses and dendritic spines linked to cognitive alterations in schizophrenia (Lin et al., 2019). The clinical meta-analysis yielded 81 variants in 11 loci ...

Their synapse formation is also altered ... within disorders like schizophrenia and autism. It has also been implicated in a variety of degenerative conditions. The most widely-studied ...