Summary: Atomoxetine is a methylphenoxy-benzenepropanamine derivative with antidepressant activity and is thought to enhance noradrenergic function via selective inhibition of the presynaptic ...

Agents that affect the CNS, including antidepressants and antipsychotics, are often prescribed for patients undergoing surgical procedures. The results of a recent survey conducted at a large ...

It is hypothesized that cortical neuronal circuits operate in a global balanced state, i.e., the majority of neurons fire irregularly by receiving balanced inputs of excitation and inhibition.

NKCC1 and KCC2 jointly regulate Cl − homeostasis in neurons and thus affect the function of the GABAergic system (Côme et al., 2020). In the early stages of development, because the expression level ...

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

Division of Evolution, Infection & Genomic Sciences, University of Manchester, Manchester M13 9PL, U.K. Division of Evolution, Infection & Genomic Sciences, University of Manchester, Manchester M13 ...

Figure 2 Subgrouping of patients with neuropathic pain according to sensory profiles from patient-reported outcomes ...