The current pathophysiology of COPD encompasses three main characteristics: emphysema, chronic bronchitis and small airway disease. Macrophages and neutrophils are implicated in this process ...

EMA accepts for review GSK’s application to expand use of Nucala for COPD treatment: London, UK Wednesday, March 26, 2025, 11:00 Hrs [IST] GSK plc announced that the European Me ...

Recent studies are, however, illustrating that three different mechanisms of airflow obstruction play a role in COPD pathogenesis. The first is the loss of support of the small airways in ...

Beam Therapeutics announced positive initial data for BEAM-302 in the Phase I/II trial in Alpha-1 Antitrypsin Deficiency (AATD).

In March 2025, Vertex Pharmaceuticals Incorporated announced a study is to evaluate the safety, and tolerability and efficacy ...

Cellular senescence contributes to the pathophysiology of chronic obstructive pulmonary disease (COPD) and cardiovascular disease. Using endothelial colony-forming-cells (ECFC), we have demonstrated ...

Introduction COPD is a chronic, progressive, inflammatory disease of the lungs and the third leading cause of death worldwide. The current knowledge of the pathophysiology of COPD is limited and novel ...

Owing to the small number of subjects, the findings related to the pathophysiology of COPD were very limited. The temporal resolution of IO is determined mainly by the duration of the oscillatory ...

Chronic inflammation of the airways, lung parenchyma, and pulmonary vasculature is a hallmark of COPD, involving inflammatory cells such as neutrophils, macrophages, and T-lymphocytes in the disease’s ...

Ginkgo biloba benefits have been claimed for centuries, with health treatments meant to help improve cognitive function and treat asthma, COPD, and bladder disorders. Studies suggest that it acts on ...