MR = Mineralocorticoid receptor; PR = Progesterone receptor. The relative binding affinity (%) of the main progestins discussed in this paper for the different steroid receptors is indicated.

[24] On contact with the receptor, the steroid-receptor complex translocates ... the systemic agents with the least mineralocorticoid activity (sodium and water retention) should be used.

The primary naturally occurring mineralocorticoid is aldosterone ... as the time of onset is similar [4]. Inhaled steroids, like budesonide, have different indications and evidence.

14 Centre for Liver and Gastroenterology research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK 15 NIHR Biomedical Research Centre, University of Birmingham and ...

2 Dept of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK Correspondence to: Dr S F Ahmed, Dept of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK; ...

RECETOX, Faculty of Science, Masaryk University, Kotlarska 2, 61137 Brno, Czech Republic ...