However, due to a low clinical ... from cervical intraepithelial neoplasia to squamous cell carcinoma. Expression of E6/E7 oncogenes increases with the severity of the lesion.

AIS: Adenocarcinoma in situ; CIN: Cervical intraepithelial neoplasia ... A large majority of high-grade lesions in the female genital tract emerge as monoclonal cell populations derived from ...

These features were absent from nondysplastic areas, but were present in 56% of low-grade intraepithelial neoplastic lesions. Importantly, there was close agreement between histopathologic and NBI ...