Organoids are made to model human organs and are promising for research and therapy, but there are limitations to their growth and function. A recent study by researchers at The University of Tokyo ...

Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination strategy. Adding immunotherapy to a new type of ...

To prevent or treat these conditions through targeted immunotherapy, we developed a clinical-stage nanoparticle platform that leverages the tolerogenic capacity of liver sinusoidal endothelial ... T ...

This review explores how the body processes ethanol and how alcohol consumption contributes to diseases affecting the liver, gastrointestinal tract, pancreas, and gallbladder. The liver is the primary ...

This review aims to provide an overview of ethanol metabolism and the diseases caused by alcohol consumption, with a focus on the liver, gastrointestinal tract, pancreas, and gallbladder.

The significance of the findings is valuable, with implications for immunotherapy design in pancreatic ductal adenocarcinoma. The evidence was considered incomplete and partially supportive of the ...

Centre for 3D models of Health and Disease, Division of Surgery and Interventional Science, University College London, London W1W 7TY, U.K. Centre for 3D models of Health and Disease, Division of ...

Silexion Therapeutics' Latest Data Demonstrates that Subcutaneously Administered SIL204 Reduces Both Primary Tumors and Metastases in Clinically Relevant Orthotopic Models Where Human Pancreatic ...

Drug discovery, pancreatic beta-cell regeneration – Olov Andersson's Group Unit of Biostatistics – Matteo Bottai Research groups in cardiology and cardiovascular diseases Sleep, cognition and health – ...

In this study, we first established two clusters that grouped pancreatic cancer cases according to their pathological characteristics and molecular markers based on PARGs. In addition, we constructed ...