Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...

Every second, an adult generates around five million new blood cells to replace aging or dying ones, making the blood system a highly regenerative organ.

Tucked away in Room 112A of the Biomedical Center, a select group of students can be found spending hours each week cultivating human stem cells. The 15 students taking BIOL 0610: “Modeling Human ...

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... Feb. 4, 2025 — Researchers have ...

Harvard Professor and Broad Institute member Paola Arlotta received the Momentum Award from the International Society of Stem ...

Researchers at the Francis Crick Institute have identified genetic changes in blood stem cells from frequent blood donors that support the production of new, non-cancerous cells. Understanding the ...

To further explore these findings, the team introduced both leukemic and non-leukemic DNMT3A mutations into human stem cells and examined their behavior in different environments. The genetically ...

The pluripotent and multipotent stem cells are found in the bone marrow, which can differentiate into any tissue in the body.

Human aging significantly contributes to cognitive decline and increased susceptibility to late-life neurodegenerative diseases (e.g.Alzheimer’ s disease, ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...