CRISPR system variant shows a novel DNA cleavage mechanism
Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...
Armed robbery in Revesby1d
DNA Cleavage Mechanism in CRISPR-Cas5-HNH Unveiled
A study published in Nature Communications and conducted by researchers from the Institute of Physics of the Chinese Academy of Sciences revealed new ...
Gene editing approach sheds light on how mitochondria drive autophagy
Autophagy is the process by which cells digest and renew their internal structures, recycling damaged or malfunctioning ...
Uncovering novel transcriptional enhancers in neuronal development and neuropsychiatric disorders
Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...
Activating complex regions of the genome to treat rare diseases: Researchers identify a a master epigenetic switch
Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...
The EMBO Journal2d
Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation
In 2020-2021, a mysterious skin disease affected fishermen in Senegal. High levels of Portimine A toxin, produced by the ...
technologynetworks2d
CRISPR Could Offer New Hope for Prader-Willi Syndrome
By activating a master epigenetic switch using CRISPR, naturally suppressed genes can be turned on, offering hope for ...
EurekAlert!2d
Researchers at IRB Barcelona discover how mitochondria drive autophagy
Headed by Drs. Antonio Zorzano and Saska Ivanova, a study published in the journal Autophagy unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing ...
Morocco World News4d
Gene Editing for Growth: How CRISPR Could Redefine Africa’s Agricultural Landscape
Africa is grappling with severe food insecurity in the wake of consecutive droughts, climate change, and ongoing conflicts, ...