However, existing BBB models have been unable to replicate the complex three-dimensional 3D structure of cerebral blood vessels, posing significant challenges for research and drug development.

SIL-204's ability to reduce primary tumor growth when administered systemically in orthotopic pancreatic cancer models, where human tumor cells are implanted directly into the pancreas SIL-204's ...

The growth of healthy tissues in the body depends on the development of new blood vessels ... dCNP in several mouse solid tumor models, including pancreatic, colon, lung, and mammary ...

But in clinical trials, drugs, especially cancer therapies, often fail. That may be because cancer models are inadequate and do not reliably replicate the tumor environment. Neuroscientist Ronit ...