A hidden strategy: How SARS-CoV-2 uses fibrinogen to evade the immune system
As scientists, we often think we understand a virus—its structure, its tricks, the way it moves through the body. But every ...
dvm3605d
Highly pathogenic avian influenza and biosecurity
Christopher Lee, DVM, MPH, DACVPM, explains why early detection and enhanced biosecurity are essential for mitigating the spread of highly pathogenic avian influenza ...
Hosted on MSN15d
H5N1 influenza viral lineages beginning to evade human immunological defenses, research finds
researchers find "the continuous transmission of H5N1 from birds to mammals and the increase in strains with immuno-evasive HA in mammals sampled over time suggest that antigenic drift is a source of ...
Poultry's Avian Flu may mutate to humans as government dithers on biosecurity, experts warn
South African poultry industry suffers R1. 8 billion in losses as experts warn of potential human transmission risks from the current avian influenza outbreak. Government faces criticism over ...
EurekAlert!16d
H5N1 influenza viral lineages beginning to evade human immunological defenses, UNC Charlotte research finds
New computational modeling of avian influenza variants’ immunoprotein interactions – developed by a research team at the University of North Carolina at Charlotte – reveals the H5N1 influenza virus is ...
eLife16d
Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective
Conversely, this would also reveal how this selective immune pressure drives the evolutionary pathways of antigenic drift in targeted pathogens 7–10. Knowledge of the precise antibody sequences, as ...
eLife21d
The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020
Validation that K432E and I321V are responsible for antigenic drift was not determined in a background strain with native K432 and I321 or the restitution of antibody binding by reversion to K432 and ...
Medscape3mon
The Evolving History of Influenza Viruses and Influenza Vaccines
Expert Rev Vaccines. 2013;12(9):1085-1094. It became obvious that it was necessary to modify regularly the composition of the vaccine, and that it was necessary to use vaccine strains selected ...
Frontiers1y
Establishment and application of a VP3 antigenic domain-based peptide ELISA for the detection of antibody against goose plague virus infection
In this study, bioinformatics software was used to analyze and predict the dominant antigenic regions of the main protective antigen VP3 of GPV. Three segments of bovine serum albumin (BSA) ...