Courtesy of Michael Dustin PASS IT ON: A T cell (blue) interacts with a dendritic cell (yellow) through a molecular pattern described as an immunological synapse (red = adhesion, green = foreign ...

Immunological synapse (IS) formation is a key part of developing and sustaining immune responses against cancer and is necessary for T cells and NK cells to eliminate tumor cells. This webinar will ...

How might the immune system take advantage of the B cell synapse to optimize the effectiveness of encounters between B cells and soluble toxin or circulating viruses? The answer may lie ...

The interaction between CD2 and CD58 is critical for forming the immunological synapse, which is pivotal in immune cell activation and adhesion, as well as signaling in both immune and target cells.

When a B cell encounters membrane-bound antigen, signalling through the B-cell receptor (BCR) induces cytoskeletal reorganization and morphological changes that lead to the formation of an ...

CTLs and NK cells kill by forming a stereotyped interface with their targets, known as a cytolytic immunological synapse, into which they secrete a mixture of toxic perforin and granzymes. Our ...