Imaging the actin cytoskeleton in presynapses is not easy as the abundance of the protein in the postsynaptic terminal often obscures its presence in the presynaptic one, Leterrier explained. Genome ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Neuroligin-1 is found on the postsynaptic side of excitatory synapses 5, and neurexins may be primarily localized to the presynaptic membrane, although definitive evidence is lacking. Serafini and ...

Between impulses the transmitter molecules are rapidly removed from the synaptic cleft to prevent continuous stimulation of postsynaptic ... reabsorbed back into the presynaptic neuron and ...

Synapse formation is driven by a host of different cell adhesion molecules. One of the most recent to be identified is leucine-rich repeat transmembrane neuronal protein 2 (LRRTM2). Two papers now ...