A plasmid is a small, circular, double-stranded DNA molecule that is distinct from a cell's chromosomal DNA. Plasmids naturally exist in bacterial cells, and they also occur in some eukaryotes.

The ability to control gene expression across a wide range is crucial for many fields, including bioengineering, disease detection, and environmental monitoring. Research led by Lingchong You, Ph.D., ...

Imunon has reported new immunogenicity and safety data from its proof-of-concept Phase I trial’s ongoing analyses of the IMNN-101 DNA plasmid vaccine. The investigational vaccine, based on the company ...

Plasmid DNA is an essential part of cell and gene therapy products. It is utilized as a template vector for cell therapy and non-viral gene therapy and as a raw material to produce adeno-associated ...

In animals, effective immune responses against malignancies and against several infectious pathogens, including malaria, are mediated by T cells. Here we show that a heterologous prime-boost ...

Discover the price reduction of ENFINIA™ DNA products by 25%, improving access to high-quality DNA for researchers.

Plasmids come in different sizes and conformations, and so confirming and verifying plasmid quality is essential for downstream use. Scientists commonly do this using gel electrophoresis analysis, ...

Price drop reflects efficiency gains from Co.’s cell-free cloning tech & new facility, where automation & ML have increased ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...

Cell debris was removed by centrifugation and plasmid was precipitated by 0.7 volume of isopropanol. The pelleted DNA was resuspended in 400 μl of 10 mM Tris HCl, pH 8.0 and precipitated with an ...