This is worthwhile as antibodies are often raised against relatively preserved domains and may recognize your target even if the sequence homology of the epitope is as low as 75%. 2 The different ...

The properties of the different IgG isotypes should be considered in developing therapeutic antibodies ... IgG3, IgE and IgM. The evolutionary advantage of functional monovalency is also evident ...

or an IgM-positive ELISA plus either an IgG titer that increased by a factor of 4 or more (to ≥1:128) on IFA or seroconversion from an IgG-negative ELISA to an IgG-positive ELISA between the ...

IgM, IgD, IgA, IgG, IgG1, 2, 3, and 4, and total IgE were measured ... interactions with the innate immune system, and a secondary antibody response. These alterations may have a role in the ...

Optimized subcutaneous administration of BHV-1300 achieved rapid, deep and sustained lowering of IgG, differentiating Biohaven's new small molecule class of degraders from the monoclonal antibody ...

Optimized subcutaneous administration of BHV-1300 achieved rapid, deep and sustained lowering of IgG, differentiating Biohaven's new small molecule class of degraders from the monoclonal ...