O’Brien isn’t the only newcomer joining the world of anthropomorphic toys in “Toy Story 5.” Anna Faris has been cast in an undisclosed role, and Ernie Hudson will take over as action figure Combat Carl after the OG voice actor, Carl Weathers, died at age 76 in 2024.

Conan O'Brien finds lots of friends and joins the Toy Story 5 cast as a mysterious new character named Smarty Pants.

The studio announced Monday that Conan O’Brien has been added to the film’s voice cast as Smarty Pants, a character that is new to the animation franchise. Andrew Stanton is directing Toy Story 5 alongside co-director McKenna Harris, while Jessica Choi produces the film.