Health officials on Saturday said they have identified the first U.S. case of an mpox strain that has recently prompted global health alerts over concerns about its spread, severity and transmissibility.

The United States’ first known case of a more severe strain of mpox was confirmed in California, the US Centers for Disease Control and Prevention said Saturday. The risk of clade I mpox to the public remains low,

The first case in the U.S. of a more severe strain of mpox was reported in San Mateo County, the California Department of Public Health said.